Rheumatoid pneumoconiosis (Caplan's syndrome) with a classical presentation.

نویسندگان

  • Eduardo Mello De Capitani
  • Marcelo Schweller
  • Cristiane Mendes da Silva
  • Konradin Metze
  • Elza Maria Figueiras Pedreira de Cerqueira
  • Manoel Barros Bértolo
چکیده

Although rare, rheumatoid pneumoconiosis, also known as Caplan's syndrome, can occur in workers exposed to silica, as well as in patients with silicosis, coal workers' pneumoconiosis or asbestosis. Prevalence is higher among patients with silicosis, despite the fact that it was originally described in coal workers with pneumoconiosis. The classical finding that defines this syndrome is that of rheumatoid nodules in the lungs, regardless of whether there are small rounded opacities suggestive of pneumoconiosis or large opacities consistent with massive pulmonary fibrosis, with or without clinical rheumatoid arthritis. We describe the case of a female patient with rheumatoid arthritis, diagnosed 34 years after 7 years of occupational exposure to silica at a porcelain plant. A chest X-ray showed circular opacities of 1-5 cm in diameter, bilaterally distributed at the periphery of the lungs. A CT-guided thoracic punch biopsy of one of those nodules revealed that it was rheumatoid nodule surrounded by a palisade of macrophages, which is typical of Caplan's syndrome. Aspects of diagnosis, classification and occurrence of this syndrome are discussed, emphasizing the importance of the occupational anamnesis of patients with rheumatoid arthritis and lung opacities on chest X-rays.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Influence of rheumatoid factor in coalminers' pneumoconiosis in the Fujian Shaowu colliery, south China.

Coalminers' pneumoconiosis may be complicated by the development of progressive massive fibrosis (PMF) or by rheumatoid pneumoconiosis (Caplan's syndrome).'2 The arthritis in Caplan's syndrome may precede, coincide with, or follow the development of pulmonary radiological shadows. These conditions are common in miners and may be seen in workmen exposed to dusts other than coal.' The Fujian Shao...

متن کامل

Serum protein fractions in rheumatoid pneumoconiosis without arthritis.

Fractionation of the serum proteins by filter-paper electrophoresis in 14 coal-miners who had the characteristic radiological opacities of rheumatoid pneumoconiosis but no evidence of rheumatoid arthritis showed a reduction in the mean level of albumin and increases in the alpha-2 and gamma-globulins compared with the values in non-arthritic miners with simple coal-workers' pneumoconiosis and i...

متن کامل

Caplan's Syndrome Related to Rheumatoid Factors

The rheumatoid pneumoconiosis syndrome was originally described as a characteristic chest radiographic appearance in coal-workers associated with clinical rheumatoid arthritis (Caplan, 1953). This association was later confirmed as real and not fortuitous by Miall, Caplan, Cochrane, Kilpatrick, and Oldham (1953) using an unselected population. The original communication defined the radiographic...

متن کامل

Rheumatoid Pneumoconiosis in Association with Asbestosis.

In 1953 a new syndrome was described in which the association of rheumatoid arthritis with nodular fibrosis of the lung parenchyma was noted (Caplan, 1953). Though this condition resembles progressive massive fibrosis in some ways, there are certain distinctive features. The opacities that are found in Caplan's syndrome are usually more peripherally situated, tend to be multiple, and more commo...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia

دوره 35 9  شماره 

صفحات  -

تاریخ انتشار 2009